| Tuesday, January 11, 2011 |
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Monitoring Functional Nanoparticle Toxicity
As nanoparticle use in consumer
products and medical applications continues to increase drastically, the field
of nanotoxicology has developed to examine the impacts of these nanoparticles
in biological systems. Unfortunately, much of the toxicity assessment that has
been performed to date is limited to considerations of in vitro cell viability,
ignoring functional changes that may occur in surviving nanoparticle-exposed
cells. The work presented herein
will detail a method to monitor the critical cell function of exocytosis
following nanoparticle exposure under a myriad of conditions, including varied
nanoparticle material, surface charge, concentration, and mesostructure.
In addition, mechanisms of toxicity,
such as the generation of reactive oxygen species, that may induce functional
changes will also be discussed.
About the Speaker
Dr. Christy Haynes is an associate professor in the chemistry department at the University of Minnesota. She completed her undergraduate work at Macalester College in St. Paul, MN (1998) with a major in Chemistry and minors in Mathematics and Spanish. Dr. Haynes’ doctoral work was done at Northwestern University in Evanston, IL (2003) under the direction of Richard P. Van Duyne.
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Map to Tamarack Nature Center |
| Schedule: Executive Committee Meeting, 5:00 PM Dinner, 6:00 PM Talk, 7:00 PM
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Directions:
Tamarack is located about 20 minutes from Downtown St. Paul, Minnesota. From Downtown St. Paul, take I-35E North to Highway 96, go east on Highway 96 to Otter Lake Road, go north. Tamarack is located approximately 2½ miles on the left-hand side at 5287 Otter Lake Road.
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